Figure 4.

Effect of CAPs exposure on mucus hypersecretion and BALF protein. Animals were sensitized and challenged with saline (white bars) or with OVA (black bars) immediately prior to exposure to CAPs in Grand Rapids (A, B), or Detroit (C, D). Twenty four hours after the CAPs exposure bronchoalveolar lavage fluid was collected and content of total protein and mucin glycoprotein 5 AC were determined as described in Methods. * = significantly different from respective group challenged with saline; ** = significantly different from respective group exposed to filtered air; n = 8/group; p < 0.05.