Figure 5. Summary of the functional domains of S. pombe Rap1.

(A) The interaction domains of Rap1 with its partners are shown in the upper part. Dark green bars indicate the regions responsible for each telomere function. Pale green bars indicate the regions whose involvement in each telomere function is unclear. The Rap1-interactors required for each telomere function are indicated at the right. (B) Sequence similarity between S. cerevisiae Rap1 (ScRap1), S. pombe Rap1 (SpRap1), and human Rap1 (HsRap1). Identity (indicated in black) and similarity (indicated in grey) of the amino acid sequences between the homologous domains were analyzed by the ClustalW program.