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. 2012 Nov 2;7(11):e47725. doi: 10.1371/journal.pone.0047725

Table 3. Association between the different types of virological response and the genetic variants assessed.

Genotype/allele RVR (n = 35) EVR (n = 73) SVR (n = 51)
OR (95%CI) p OR (95%CI) p OR (95%CI) p
IL28B rs8099917 TT 1 1 1
GT 0.41 (0.14–1.23) 0.1 0.42 (0.15–1.21) 0.25 0.35 (0.14–0.87) 0.01
GG 0 0.44 (0.04–5.39) 0
T 2.8 (1.1–7.58) 0.03 1.9 (0.84–4.46) 0.12 3.1 (1.41–6.79) 0.004
CTLA4 rs231775 AA 1 1 1
AG 0.29 (0.09–1) 0.03 0.78 (0.27–2.21) 0.46 0.36 (0.08–1.72) 0.23
GG 0.13 (0.01–1.11) 3 (0.33–26.79) 0.74 (0.16–3.35)
A 3.6 (1.44–9) 0.004 0.8 (0.37–1.76) 0.6 1.16 (0.6–2.27) 0.66

RVR: Rapid virological response. EVR: Early virological response. SVR: Sustained virological response. OR: Odds ratio. CI: confidence interval.

Odds ratio in the different genotypes are referred to the genotype with OR = 1. The value “0” means that there were no subjects carrying this genotype.

Note: the remaining genetic variants assessed showed no significant associations with RVR, EVR and SVR (p>0.05 for all comparisons).