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. 2012 Nov 2;7(11):e47725. doi: 10.1371/journal.pone.0047725

Table 4. Association of clinical, biochemical, and therapeutic factors with SVR in patients who completed the scheduled 48-week treatment regimen with pegIFNα and ribavirin.

Variables Odds ratio 95% CI p
Male vs. female 2.33 0.91–5.96 0.07
Age ≤40 vs. >40 years 2.17 0.97–4.85 0.06
Weight<75 vs. ≥75 Kg 0.48 0.19–1.18 0.1
CDC stage B vs. A 0.66 0.2–2.17 0.49
CDC stage C vs. A 0.42 0.14–1.26 0.12
HIV viral load<200 vs. ≥200 copies/mL 1.39 0.55–3.5 0.48
HAART (yes vs. no) 0.9 0.33–2.66 0.9
ABC (yes vs. no) 1.46 0.5–4.17 0.48
HCV RNA>800000 vs. ≤800000 IU/mL 0.9 0.4–2.02 0.8
HCV RNA>600000 vs. ≤600000 IU/mL 0.69 0.3–1.56 0.37
HCV RNA>400000 vs. ≤400000 IU/mL 0.54 0.2–1.44 0.22
HCV genotype 2+3 vs. 1+4 4.65 1.85–11.6 0.001
Fibrosis 2–4 vs. 0–1 1.35 0.56–3.3 0.5
Steatosis (yes vs. no) 1.39 0.31–6.14 0.7
CD4≤350 cells/mL 2.96 0.87–10 0.07
EVR (yes vs. no) >999.999 <0.001
RVR (yes vs. no) 31.2 6.56–148.37 <0.001
pegIFNα 2a vs pegIFNα 2b 1.4 0.65–3.17 0.37

pegIFNα: pegylated interferon alpha. CI: confidence interval. CDC: Centers for Disease Control.

HAART: highly active antiretroviral therapy. ABC: abacavir. EVR: early virological response. RVR: rapid virological response.