Table 7. Independent predicitive factors of adverse effects.
Neutropenia | Thrombocytopenia | ||||
OR (95%CI) | p | OR (95%CI) | p | ||
PegIFNα 2a vs. 2b | 4.23 (1.59–11.23) | 0.04 | 2.62 (1.91–6.29) | 0.03 | |
Female vs. male | 2.51 (0.94–6.74) | 0.07 | * | * | |
CD4 cell count ≤350 vs. >350 cells/mL | 4.69 (1.29–17.24) | 0.02 | 1.94 (0.58–6.49) | 0.28 | |
SOCS3 rs4969170 | GG | 1 | 1 | ||
AG | 0.26 (0.09–0.75) | 0.01 | 0.75 (0.31–1.83) | 0.53 | |
AA | 1.1 (0.28–3.9) | 0.94 | 0.07 (0.008–0.57) | 0.01 |
OR: odds-ratio. CI: Confidence interval. pegIFNα: pegylated interferon alpha.
Gender was not included in multivariate analysis of thrombocytopenia, because in the univariate analysis this variable did not fulfill criteria for inclusion in the multivariate analysis.