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. 2012 Nov 2;7(11):e47725. doi: 10.1371/journal.pone.0047725

Table 7. Independent predicitive factors of adverse effects.

Neutropenia Thrombocytopenia
OR (95%CI) p OR (95%CI) p
PegIFNα 2a vs. 2b 4.23 (1.59–11.23) 0.04 2.62 (1.91–6.29) 0.03
Female vs. male 2.51 (0.94–6.74) 0.07 * *
CD4 cell count ≤350 vs. >350 cells/mL 4.69 (1.29–17.24) 0.02 1.94 (0.58–6.49) 0.28
SOCS3 rs4969170 GG 1 1
AG 0.26 (0.09–0.75) 0.01 0.75 (0.31–1.83) 0.53
AA 1.1 (0.28–3.9) 0.94 0.07 (0.008–0.57) 0.01

OR: odds-ratio. CI: Confidence interval. pegIFNα: pegylated interferon alpha.

*

Gender was not included in multivariate analysis of thrombocytopenia, because in the univariate analysis this variable did not fulfill criteria for inclusion in the multivariate analysis.