Table 4.

Correlation between grading and staging of chronic hepatitis and protein kinase R in liver tissue

	PKR gene expression in liver
	GII (HCV-4)		GIII (HCV-4 related HCC)
Spearman's correlation coefficient	rs	P-value	rs	P-value
HAI	0.83	0.0001	0.89	0.0001
Fibrosis	o.56	0.004	0.84	0.0001

A significant positive correlation is obvious in which higher HAI and fibrosis scores are associated with high rate of PKR gene expression.

GII (HCV-4): group II with hepatitis C virus genotype 4; GIII (HCV-4 related HCC): group III with hepatitis C virus genotype 4 related hepatocellular carcinoma; HAI: histological activity.

Index; PKR: protein kinase R.