Table 4. Brain regions demonstrating significantly reduced cortical thickness in aMCI two years later.

Cluster no.	Region name	L/R	Peak MNI coordinates (x,y,z)	Peak t value	Number of vertices in cluster	RFT-corrected p value for cluster
1	Cingulum_Post	L	−2,−50,15	6.1246	96260	2.177e-08
	ParaHippocampal	L	−22,−14,−22	8.1999
	Temporal_Pole_Sup	L	−24,−1,−40	7.4084
	Temporal_Pole_Mid	L	−30,−4,−36	7.4984
	Temporal_Sup	L	−51,0,−24	6.8052
	Temporal_Mid	L	−60,−2,−22	7.2870
	Temporal_Inf	L	−30,−11,−38	7.0859
	Frontal_Sup_Medial	L	−20,60,22	4.5265
	Angular	L	−49,−63,41	4.9026
2	Frontal_Sup_Orb	R	10,66,9	4.4252	99789	2.177e-08
	Olfactory	R	17,8,−17	5.6264
	Cingulum_Post	R	4,−53,19	6.4628
	ParaHippocampal	R	25,−10,−24	8.0334
	Temporal_Pole_Sup	R	21,2,−36	7.3326
	Temporal_Pole_Mid	R	27,−3,−38	7.6556
	Temporal_Mid	R	48,1,−36	6.9493
	Temporal_Inf	R	43,−2,−46	7.1703
	Temporal_Sup	R	50,−11,−17	6.2965
	Fusiform	R	37,−21,−31	6.6532
	Angular	R	45,−57,9	4.9855
	Precuneus	R	4,−53,19	6.4641

Note: The meanings of Peak t value and Peak MNI coordinates are the same as Table?.