Table 1. Time (seconds) needed to complete one update of all coordinates and to reach convergence in sets of gene expression data from blood disorders.

		rNMF		control
Data set, reference	Data size	iteration	convergence	iteration	convergence
Acute Myeloid Leukemia [36]	22283×293	0.75	21.7	2.2	219.4
Acute Myeloid Leukemia [37]	54613×461	3.95	128.8	10.2	>600
Acute Myeloid Leukemia [38]	44692×162	0.96	17.3	1.5	163.6
Acute Lymphoblastic Leukemia [39]	22215×288	0.94	17.8	2.3	245.7
Multiple Myeloma [40]	54613×320	3.04	29.1	6.4	>600

All methods were implemented in C++ and identically initialized. Timings obtained on a 2.30 GHz Intel Core i7 2820QM CPU with 16 GB RAM. For convergence, we required a relative decrease in the objective function less than 10 in successive iterations. Throughout, and .