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. 2012 Jun 22;13(1):53. doi: 10.1186/1465-9921-13-53

Table 3.

Mean ratios (between AZD8848 and placebo) for levels of α2-macroglobulin and tryptase, respectively, in nasal lavages obtained 24 hours after the last allergen challenge in the repeat challenge/treatment study

Variable Mean ratio 95% CI P-value
α2-Macroglobulin
 0.50
 0.25-0.97
 0.020
Tryptase 0.62 0.35-1.10 0.049

α2-Macroglobulin was reduced in patients who had received AZD8848 (p < 0.05, c.f. placebo). Similarly, lower levels of tryptase were observed in this group (p < 0.05, c.f. placebo).