Table 4.
Salvage treatment for recurrent OCC following initial surgery
| Author [ref] | Center | Year | Interval | N recurrences after surgery alone | IMRT |
OAS rate after salvage therapy |
|
|---|---|---|---|---|---|---|---|
| Surgery (+/−RT) | RT (+/−CT) | ||||||
| Schwartz et al [8] |
U of Illinois, Chicago |
2000 |
1956-1992 |
38 (28%) |
no |
~25% at 5y (n = 27) |
0% at 1y (n = 11) |
| Koo et al [9] |
Yonsei U, Seoul |
2005 |
1991-2003 |
36/127 (28%) |
no |
~25% at 5y (n = 13) |
0% at 2y (n = 10) |
| Liu et al [10] |
U of Taiwan |
2007 |
1995-2003 |
224 (na) |
no |
34% at 5y (n = 326)∗ |
21% at 2y (n = 75)∗ |
| Kokemueller et al [11] |
U of Hannover |
2011 |
1980-2009 |
115/341 (37%) |
no |
~25% at 5y (n = na) |
10% at 4y (n = na) |
| own group |
U hospital of Zurich |
2012 |
2002-2011 |
38 (na) |
yes |
55% at 5y (n = 28) |
30% at 5y (n = 10) |
| 75% at 5y (n = 18)∗∗ | 25% at 5y (n = 20)∗∗ | ||||||
∗: outcome of recurrent OCC following surgery alone (n = 224) and surgery + RT/CT (n = 177).
∗∗: results when analyzed according to ‘salvage IMRT for R0-1 situations’ versus ‘salvage IMRT for macroscopic disease’. U: University. na: not available.