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102/106 library variants identified in primary and secondary screens that catalyze farnesylation of dns-GCVDS and dns-GCVKS with enhanced efficiency
Charged residues are highlighted in bold.
| Reactive with dns-GCDVS |
Reactive with dns-GCVKS |
||
|---|---|---|---|
| 102 | 106 | 102 | 106 |
| Leu | Arg | Leu | Glu |
| Arg | Leu | Asp | Glu |
| Lys | Arg | Phe | Glu |
| Asn | Arg | Thr | Gln |
| Lys | Tyr | Ser | Asp |
| Arg | Val | Ile | Asp |
| Lys | Asn | ||
| Lys | His | ||
| Lys | Ile | ||
| Ile | Lys | ||
