TABLE 4.
Structural homologues of the two EpfN domains EpfN1 and EpfN2
The Protein Data Bank (PDB) was searched using SSM (29), and the most closely related structures are listed here with their ligand (if reported). rmsd, root mean square deviation; Nalg, number of aligned Cα positions; SI, sequence identity; NA, not applicable.
| Protein | Ligand | Organism | rmsd | Nalg | SI | PDB | Reference |
|---|---|---|---|---|---|---|---|
| Å | % | ||||||
| EpfN1 | |||||||
| Epha7 ligand-binding domain | Ephrin | Homo sapiens | 2.76 | 125 | <10 | 3NRU:K | NA |
| XG34 CBM | Xyloglucan | Rhodotermus marinus | 3.09 | 134 | <10 | 3JXS:B | Ref. 49 |
| Xylanase CBM4-2 | Xylan | Rhodothermus marinus | 2.89 | 128 | <10 | 1K45:A | Ref. 51 |
| Laminarinase CBM4 | Laminarin | Thermotoga marina | 2.71 | 118 | <10 | 1GUI:A | Ref. 52 |
| EpfN2 | |||||||
| Fibronectin type III domain | Homo sapiens | 2.42 | 76 | <10 | 2HA1:A | Ref. 43 | |
| FnIII domain of CDO | Desert hedgehog protein | Homo sapiens | 2.85 | 86 | <10 | 3D1M:D | Ref. 50 |
| FnIII domain NCAM1 | Homo sapiens | 2.68 | 86 | <10 | 2E3V:B | NA | |
| CHIR-AB1 | IgY | Gallus gallus | 2.46 | 80 | <10 | 2VSD:A | Ref. 53 |