Transcriptional response of ARG3 and ARG5,6 promoters in an arg82Δ strain rescued with IPMK homologues. Quantification of ARG5,6 promoter strength was determined as indicated in Fig. 5A. arg82Δ was rescued with an Arabidopsis IPMK homologue (AtIpk2β), its kinase-dead (KD) variant (AtIpk2β-D/A), the human IPMK homologue (hIPMK), or a kinase-dead version (hIPMK-DK/AA). Error bars correspond to S.E. The statistical analysis was performed using a two-tailed and homoscedastic t test (***, p < 0.001; NS, not significant).