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. 2012 Sep 19;287(45):38356–38366. doi: 10.1074/jbc.M112.377382

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© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 7. — Effects of the defective IL-11/IL-11Rα signaling axis on SmoM2-mediated carcinogenesis. A, typical H&E staining images of skin specimens from tumor-bearing mice with IL-11Rα^+/+, IL-11Rα^+/−, or IL-11Rα^−/−, with the thickness shown by the bars. B, average epidermal thickness, a measure for BCC tumor size, from mice with different genotypes. p < 0.05 indicates statistically significant. C, expression of phosphorylated STAT3, cyclin D1, total STAT3, and β-actin in skin tissues from different genotypes.