Table-1.
Sample characteristics of participants included in the 15O-water PET studies (BLSA neuroimaging substudy)
| rs11136000 Genotype | N | APOE ε4 status | Sex | Race | Education (years) (±SD) | Age at baseline (years) (±SD) | Follow-up duration (years) (±SD) | Framingham Risk Score (±SD) |
|---|---|---|---|---|---|---|---|---|
| Whole Sample | 88 | 59 ε4− 29 ε4+ |
36 F 52 M |
78 C 10 AA |
16.4 (2.8) | 69.3 (7.3) | 7.5 (0.9) | 13.4 (7.5) |
| CC | 29 | 21 ε4− 8 ε4+ |
9 F 20 M |
28 C 1 AA |
16.7 (2.8) | 69.8 (6.5) | 7.8(0.6) | 13.9 (7.5) |
| TC | 45 | 31 ε4− 14 ε4+ |
24 F 21 M |
39 C 1 AA |
16.1 (2.5) | 69.0 (7.4) | 7.3 (1.0) | 12.1 (7.2) |
| TT | 14 | 7 ε4− 7 ε4+ |
3 F 11 M |
11 C 3 AA |
16.8 (3.5) | 69.3 (8.8) | 7.4 (0.9) | 16.8 (8.0) |
| p-value for difference | 0.32 | 0.044 | 0.13 | 0.61 | 0.88 | 0.11 | 0.13 |
F= female; M= male, C= Caucasian; AA= African-American