Table-3. Local maxima within areas of significant longitudinal increases in rCBF in carriers of the C-allele of the rs11136000 snp in the clusterin gene. Coordinates are in stereotactic space and Brodmann areas are in parentheses.

Carriers of the C-allele of the rs11136000 SNP were coded additively (CC=2, CT=1 and TT=0) in a voxel-based multiple regression analysis (SPM5).

		Coordinates
Region	side	x	y	z	t value	p value	FDR-adjusted p value	# voxels
Orbitofrontal Cortex (47)	R	34	30	−22	3.73	<0.001	0.06	130
Ant Cingulate Cortex (32)	R	14	46	4	4.13	<0.001	0.02	245
Hippocampus	R	36	−24	−14	4.10	<0.001	0.02	137
Hippocampus	L	−26	−22	−6	3.35	0.001	0.03	90