Table IV.

Adjusted odds ratios of citing specific discontinuation reasons

Discontinuation Reasons, OR (95% CI)	Systemic Treatment			Biologics			Phototherapy
	Methotrexate	Acitretin	Cyclosporine	Etanercept	Adalimumab	Infliximab	UVB	PUVA
Did not work well enougha	1.00 [ref.]	1.56 (0.97–2.46)	0.75 (0.46–1.23)	1.28 (0.89–1.83)	1.74 (1.11–2.74)	0.59 (0.30–1.15)	0.90 (0.63–1.30)	0.67 (0.39–1.17)
Worked well at first but stopped working wellb	1.00 [ref.]	0.86 (0.46–1.62)	1.43 (0.77–2.68)	5.19 (3.23–8.33)	2.10 (1.20–3.67)	2.07 (0.95–4.51)	0.88 (0.55–1.40)	1.09 (0.56–2.12)
Any side effectc,d	1.00 [ref.]	1.56 (1.08–2.25)	1.08 (0.70–1.67)	0.34 (0.23–0.49)	0.48 (0.30–0.75)	1.30 (0.78–2.17)	0.21 (0.14–0.31)	0.66 (0.41–1.06)
Cannot afford treatmente	1.00 [ref.]	2.06 (0.76–5.61)	1.47 (0.51–4.20)	1.45 (0.68–3.10)	0.83 (0.29–2.32)	0.89 (0.21–3.82)	7.03 (3.14–15.72)	2.40 (0.75–7.61)

OR, odds ratio; CI, confidence interval; UVB, ultraviolet B; PUVA, oral psoralen plus ultraviolet A

^aAdjusted for duration of psoriasis diagnosis, heavy drinking, time of last treatment use, treatment duration, and number of past treatments

^bAdjusted for treatment duration and number of past treatments.

^cIncludes non-life threatening side effects and/or life threatening side effects

^dAdjusted for age, sex, marital status, household income level, and health insurance status.

^eAdjusted for age, health insurance status, heavy drinking, psoriatic arthritis, and time of last treatment