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. 2012 Aug 31;40(20):10041–10052. doi: 10.1093/nar/gks768

Table 2.

Comparison of RNA-ensign (columns A) with multiple runs of RNAinverse (C) and NUPACK (D)

Length Probability
Entropy
Time (s)
A B C D A B C D A B C D
0–40 0.69 0.65 0.60 0.97 0.056 0.051 0.065 0.003 62 28 61 27
41–80 0.35 0.21 0.53 0.89 0.148 0.157 0.100 0.008 1883 742 711 8973
81+ 0.40 0.30 0.29 0.93 0.062 0.147 0.125 0.006 9332 2434 1269 2920

We ran RNAinverse 10 000 times and NUPACK 100 times on the RNA-STRAND dataset using random seeds (C+G content and A+G content of 50%) and reported the Boltzmann probability of the target structure and the base pair entropy of the best solution found over all runs. The total running time is indicated in seconds in the last columns. We also included the performances achieved by RNA-ensign with a number of mutations bounded by 50% (B) of the number of nucleotides.