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. 2012 Aug 24;40(20):10478–10493. doi: 10.1093/nar/gks789

Table 1.

MicroRNAs inversely altered in HCC tissues and TPA-treated HepG2 cells

microRNA name Chromosomal location Tissue miRNA levelsa
Fold-change (T versus N) Paired t-test P-value HepG2 miRNA levelsa
Fold change (TPA/DMSO) Predicted targets
Normal Tumor DMSO TPA
miR-139-5p 11q13.4 12.73 ± 0.47 10.32 ± 1.27 −5.35 1.54 × 10−7 6.72 9.25 5.79 617
miR-199a-3p 1q24.3, 19p13.2 10.83 ± 1.22 7.63 ± 2.29 −9.16 9.02 × 10−6 4.65 7.02 5.17 531
miR-101 1p31.3, 9p24.1 6.07 ± 0.84 4.98 ± 0.90 −2.13 1.48 × 10−5 5.54 7.28 3.35 1004
miR-10b 2q31.1 5.21 ± 0.73 7.20 ± 1.53 3.98 5.57 × 10−5 11.10 9.13 −3.92 329
miR-100 11q24.1 12.47 ± 0.83 10.39 ± 2.90 −4.22 5.94 × 10−3 3.90 7.74 14.36 39
miR-22 17p13.3 12.45 ± 1.53 11.41 ± 1.92 −2.06 7.08 × 10−3 6.50 8.09 3.00 459

amiRNA levels expressed as 39-Ct, Tissue miRNA levels expressed as mean ± SD.