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. 2012 Aug 30;40(20):10172–10186. doi: 10.1093/nar/gks819

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© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — SUMO-1-marked promoters are associated with genes marked with H3K4me3. (A) The Venn diagram depicts the degree of overlap between the SUMO-1-marked promoters and H3K4me3-marked promoters (left) as well as SUMO-1-marked promoters and the H3K27me3-marked promoters (right). (B) The heat maps of chromatin marks (H3K4me3, SUMO-1 and H3K27me3, respectively) on each gene ±10 kb surrounding the TSSs (bent arrow). Each row represents the corresponding tag density trace for each individual gene; rows are ordered and kept the same in each heat map according to the maximum intensity of SUMO-1 labeling in the peak region (−1600 to 400 bp) of G1-stage sample. The Pearson correlation coefficients between SUMO-1 and H3K4me3 or H3K27me3 are shown (see ‘Materials and Methods’ section).