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. 2012 Sep 8;40(20):10098–10106. doi: 10.1093/nar/gks825

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© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — The distribution of the translation time excess ratio (see main text for an explanation). It quantifies the impact of traffic jams on the average reading times of codons. A value of 1 means that there is no significant impact of traffic jams on the average reading times of individual codons. Values smaller than 1 are possible because of stochastic fluctuations. We vary the number of ribosomes (left) and the size of the transcriptome (right). Doubling either the number of ribosomes or the number of mRNAs is sufficient to effectively remove the impact of traffic jams.

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