Table 2.

Multivariable Analysis of Depression Associated With All-Cause Mortality in Stage 5 CKD Patients

	Univariate		Multivariable
Characteristics	HR	95 % CI	HR	95% CI
Major Depression	1.80	1.07–3.02	2.95	1.234–7.02
Male	1.68	1.05–2.68	1.60	0.70–3.70
Some College	1.06	0.66–1.70	1.63	0.68–3.84
Age, < 55 years	1.0	Reference	1.00	Reference
Age 55 to 64 years	1.15	0.37–3.58	1.27	0.18–8.63
Age 65 to 74 years	1.38	1.63–9.60	5.95	1.55–22.95
Age 75+ years	1.60	2.06–11.89	5.38	1.45–19.94
White	1.0	Reference	1.00	Reference
African American	0.71	0.31–1.65	0.84	0.28–2.58
Other Race/Ethnicity	1.01	0.46–2.22	1.13	0.26–4.99
Single	0.56	0.33–0.93	0.71	0.28–1.81
Body Mass Index	0.95	0.90–1.00	0.93	0.86–0.99

Models adjusted for age, sex, education, race, baseline cardiovascular disease, stroke, peripheral vascular disease, retinopathy, neuropathy, , smoking, hemoglobin A1c, body mass index, years on dialysis, sedentary lifestyle, and education.

Definitions: CKD= chronic kidney disease, HR= hazard ratio.