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. Author manuscript; available in PMC: 2012 Nov 3.
Published in final edited form as: Lancet. 2012 Feb 2;379(9820):1056–1067. doi: 10.1016/S0140-6736(11)60871-4

Table.

Prevalence, incidence, and sex differences (when reported) for major depressive disorder from large population cohort studies of adolescents by age (years)

Diagnostic interview Sample size Prevalence % (SE* or 95% CI)
Incidence
Current Lifetime
National comorbidity survey26
15–24 years (Data for 15–16 shown) CIDI 1769 7 (1·8*) 14·6 (2·6) ··
 Female CIDI ·· 12·4 23·4 ··
 Male CIDI ·· 1·5 5·7 ··

Great Smoky Mountains study27

11 years CAPA 901 1·9§ (1·0–3·5) ·· ··
13 years CAPA 833 2·6§ (1·3–5·3) ·· ··
15 years CAPA 1136 3·7§ (2·3–6·0) ·· ··
16 years CAPA 1101 3·1§ (1·8–5·3) ·· ··

Oregon adolescent depression project6

14–18 years K-SADS 1709 2·9 20·4 7·8
 Female K-SADS ·· 3·4 24·8 10·4
 Male K-SADS ·· 2·0 11·6 4·8

British child and adolescent mental health survey28

11–12 years DAWBA 1901 0·4 (0·14*) ·· ··
13–15 years DAWBA 2624 1·9 (0·28*) ·· ··

Dunedin longitudinal study25

11 years DISC-C 653 1·1|| 1·1 1·07
 Female DISC-C ·· 0·3 ·· 0·3
 Male DISC-C ·· 1·8 ·· 1·8
13 years DISC-C 2·1|| 3·2 2·1
 Female DISC-C ·· 2·2 ·· 2·2
 Male DISC-C ·· 2·1 ·· 2·1
15 years DISC-C 2·8|| 5·7 2·5
 Female DISC-C ·· 4·4 ·· 4·4
 Male DISC-C ·· 1·2 ·· 0·6
18 years DIS 16·8|| 20·7 15·0
 Female DIS ·· 23·2 ·· 20·7
 Male DIS ·· 10·8 ·· 9·6

CIDI=composite international diagnostic interview. CAPA=child and adolescent psychiatric assessment. K-SADS=schedule for affective disorders and schizophrenia for school-age children. DAWBA=development and well-being assessment. DISC-C=diagnostic interview schedule for children-child version. DIS=diagnostic interview schedule.

Current=28–30 days.

§

Current=3 months (any depressive disorder).

Current=point.

||

Current=1 year.

Timeframes refer to period over which symptoms of depression were assessed.