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. 2012 Oct 22;12:190. doi: 10.1186/1472-6882-12-190

Table 6.

Effect of Nuna kadugu on water consumption in experimental rats - repeated oral toxicity study

Treatment Sex  
  
      (ml)
  
  
1stWeek 2ndWeek 3stWeek 4stWeek 5thWeek 6thWeek
Control (0.5% CMC)
 M(n=5)
 100.80±12.45
 101.00±15.37
 100.40±6.96
 100.80±11.34
    
F (n=5)
 98.40±5.53
 101. 00±11.05
 101.80±12.68
 101.40±13.95
    
MF(n=10)
 99.60±6.43
 101.00±8.92
 101.10±6.82
 101.10±8.48
    
NK
 (300 mg/kg p.o/day)
 M(n=5)
 99.40±11.42
 100. 20±9.61
 101.20±16.83
 100.60±13.67
    
F (n=5)
 101.60±5.71
 101.40±11.28
 100.60±9.09
 101.60±11.51
    
MF(n=10)
 100.50±6.03
 100.80±6.99
 100.90±9.02
 101.10±8.42
    
(600 mg/kg p.o/day)
 M(n=5)
 98.80±11.89
 101.80±9.05
 101.00±19.24
 100.80±14.37
    
F (n=5)
 100.00±7.29
 100.80±8.00
 102.20±17.30
 100.40±11.21
    
MF(n=10)
 99.40±6.58
 101.30±5.70
 101.60±12.20
 100.60±8.59
    
(900 mg/kg p.o/day)
 M(n=5)
 99.80±9.61
 100.40±5.35
 100.20±9.44
 98.80±7.00
    
F (n=5)
 100.20±12.48
 99.80±6.97
 99.60±6.10
 101.20±16.49
    
MF(n=10)
 100.00±7.43
 100. 10±4.14
 99.90±5.30
 100.00±8.45
    
Satellite group
Control (0.5% CMC)
 M(n=5)
 101.60±8.35
 102.60±7.12
 100.80±15.63
 102.40±13.55
 101.40±10.62
 100.40±19.44
F (n=5)
 99.40±4.15
 100.20±5.84
 100.00±10.43
 99.00±5.55
 100.40±8.44
 101.60±18.25
MF(n=10)
 100.50±4.41
 101.40±4.36
 100.40±8.86
 100.70±6.93
 100.90±6.40
 101.00±12.57
NK (900 mg/kg p.o/day) M(n=5)
 101.60±8.39
 101.40±10.63
 101.60±14.66
 101.20±4.04
 102.40±11.78
 101.60±10.80
F (n=5)
 99.40±13.01
 99.80±8.26
 100.60±11.29
 101.60±11.71
 101.00±14.32
 102.20±12.29
MF(n=10) 100.50±7.31 100.60±6.35 101.10±08.72 101.40±5.84 101.70±8.74 101.90±7.71

Values expressed as mean ± SEM; ml – milleliters; Significance with Tukey’s test following one way ANOVA is evaluated as *p < 0.05 and **p < 0.01 vs control group.