Table 3.
Multivariate Cox regression analyses of prognostic factors on overall survival of 576 patients with R0/1 pancreatic resection for ductal adenocarcinoma of the pancreas
| Parameter | Category | HR | 95% CI | P-value |
|---|---|---|---|---|
| Grading |
G1 |
0.44 |
0.22 – 0.86 |
0.017 |
| |
G2 |
1 |
|
|
| |
G3 |
1.51 |
1.21 – 1.88 |
0.0003 |
| Lymph node status |
Negative |
1 |
|
|
| |
Positive |
1.52 |
1.15 – 2.00 |
0.0031 |
| Age [years] |
< 70 |
1 |
|
|
| |
≥ 70 |
1.44 |
1.15 – 1.79 |
0.0012 |
| CA 19–9 [U/ml] |
< 37 |
1 |
|
|
| |
≥ 37 |
1.54 |
1.18 – 2.00 |
0.0016 |
| AB0 blood group |
A |
1 |
|
|
| |
0 |
0.78 |
0.62 – 0.99 |
0.037 |
| |
AB |
0.82 |
0.49 – 1.38 |
0.46 |
| B | 0.81 | 0.58 – 1.14 | 0.23 |
A total of 44 patients with missing values were excluded (Likelihood-Ratio Test: p < 0.0001).
HR = hazard ratio, CI = confidence interval.