Table 4.

Association of Carotid IMT with Left Ventricular Mass/BSA after minimal adjustment (the Basic Model) and adjustment for other risk factors (theFully Adjusted Model).

Variable	Left Ventricular Mass (g/m2)
	Basic Model1 (R2=30%)			Fully Adjusted Model (R2 =40%)
	Semi-partial R2 (%)	Estimate of β ± SE	p-value	Semi-partial R2 (%)	Estimate of β ±SE	p-value
Age	1.41	−0.25 ± 0.06	< 0.0001	1.14	−0.23 ± 0.06	<0.0001
Gender (male vs. female)	19.33	11.84 ± 0.77	< 0.0001	13.34	10.06 ± 0.73	<0.0001
Cohort2 (secondary vs. primary)	0.35	−1.56 ± 0.75	0.0365	0.001	−0.15 ± 1.04	0.8880
Smoking				1.10	4.34 ± 1.09	<0.0001
Attained duration (per year)				0.36	−0.24 ± 0.11	0.0239
Mean SBP3				2.86	0.32 ± 0.05	<0.0001
Mean LDL3				0.74	−0.06 ±0.02	0.0011
Mean HbA1c3				0.00008	0.01 ± 0.40	0.9737
AER ≥300/ESRD				2.82	8.27 ± 1.30	<0.0001
Common IMT (per 0.1mm)	3.79	2.00 ± 0.29	< 0.0001	1.22	1.19 ± 0.29	<0.0001

¹Basic Model was also adjusted for MRI machine type and IMT reader.

²Cohort: secondary cohort that had diabetes for 1–15 years with mild to moderate non-proliferative retinopathy and urinary albumin excretion rate < 200 mg/dl at the DCCT baseline versus primary cohort had diabetes for 1–5 years with no related complications

³The weighted mean of the covariate values over the period of the DCCT and EDIC combined up to the time of the cardiac MRI, where the individual visit values are weighted by the interval of time between visits that differed during DCCT and EDIC.

The units are missing for SBP, LDL and Hba1c