Table 2.

Single nucleotide polymorphism rs10455872, plasma lipoprotein(a) levels and risk of coronary heart disease in the diabetic and general populations.

Populations	Risk allele frequency	Plasma Lp(a) levels (mg/dl)			Risk of CHD		Ref.
		β (95% CI)†	p-value	Variance explained (%)	Odds ratio (95% CI)	p-value
Diabetic patients	0.07	1.28 (1.08–1.48)	4.6 × 10−39	3–4	0.94 (0.69–1.28)	0.36	[23]
General populations	0.07	1.08 (1.02–1.13)	3.6 × 10−166	25	1.47 (1.35–1.60)	3.6 × 10−15	[4]
‡p-value for heterogeneity	–	–	0.06	–	–	0.006	–

^†Regression coefficients were estimated as each one copy effect of a risk allele (G-allele) for 1-standard deviation log-transformed Lp(a).

^‡The p-value was tested for heterogeneity in the association of single nucleotide polymorphism rs10455872 with plasma Lp(a) levels and risk of CHD between the diabetic and general populations.

CHD: Coronary heart disease; Lp(a): Lipoprotein(a).