Table 3.
Chromosome imbalance regions with different alteration frequency in relation to tumor stages in lung cancer
| Chromosome | Cytoband | Start site | End site | Size (Mb) | BAC number | Early stage (n=19) | Late Stage (n=21) | Difference in alteration frequency |
|---|---|---|---|---|---|---|---|---|
|
A. Asian | ||||||||
| 6 |
p21.2 |
39548717 |
39877219 |
0.32 |
13 |
0 |
Loss :62% |
62% |
| 6 |
p22.3 |
21096443 |
22252887 |
1.15 |
39 |
0 |
Gain :66% |
66% |
| 17 |
p13.3 |
2443685 |
3461082 |
1.01 |
9 |
Gain :21% |
Gain :71% |
50% |
|
B. Caucasian | ||||||||
| 2 |
p22.2-22.3 |
35262506 |
36832851 |
1.57 |
11 |
0 |
Gain :100% |
100% |
| 2 |
p25.1 |
8929622 |
11112217 |
2.18 |
16 |
Gain :14% |
Gain :100% |
86% |
| 3 |
p24.1-24.3 |
23113657 |
26730485 |
3.62 |
32 |
Loss : 7% |
Loss :60% |
53% |
| 4 |
p15.2 |
25955365 |
26477816 |
0.52 |
4 |
0 |
Gain :60% |
60% |
| 10 | q24.2-24.3 | 100717385 | 104630288 | 3.91 | 44 | 0 | Loss :100% | 100% |