Table 1.
Select important steps in unraveling genetic heterogeneity of monogenic diabetes
| Beta cell disease | Insulin resistance | ||
|---|---|---|---|
| Year | Disease | Year | Disease |
| 1992–1999 | HNF4A MODY, GCK, HNF1A MODY, HNF1B MODY, IPF MODY, Neurod1 MODY(formerly MODY 1-6) | 1988 | Type A insulin resistance |
| 1992 | MIDD | 1988 | Donohue syndrome |
| 1998 | Wolfram syndrome | 2000 | Familial partial lipodystrophy |
| 2004–2006 | Potassium channel sub-unit related PNDM | 2002 | Generalized lipodystrophy |
| 2007 | Insulin related PNDM | ||