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BAL cytokine expression in Il-1rn−/− mice after exposure to LPS. (A) CXCL1 was exclusively elevated at 24 hours (*P < 0.05) in Il-1rn−/− mice, as opposed to littermate control mice (Il-1rn+/+). (B) CXCL2 at 4 hours (*P < 0.001). (C) CXCL5 at 4 hours (*P < 0.001). (D) G-CSF expression at 24 hours (*P < 0.05), 36 hours (*P < 0.05), and 48 hours (*P < 0.01) after exposure to LPS (n = 10–19 mice per time point).
