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. 2012 Oct 25;2(5):e001554. doi: 10.1136/bmjopen-2012-001554

Table 5.

Risk of poor health-related quality of life (HRQoL), assessed with the European Organisation for Research and Treatment of Cancer QLQ-C30, among participants with cardiovascular disease reporting major burden of disease, compared with people reporting minor burden, presented as OR with 95% CI

Burden of any cardiovascular disease*
Minor burden
1166 (86%)
Major burden
192 (14%)
HRQoL aspects† Number (%) OR (95% CI)‡ Number (%) OR (95% CI)‡
Poor global quality of life 171 (15) 1.00 (reference) 80 (42) 2.09 (1.21 to 3.60)
Poor physical function 515 (44) 1.00 (reference) 160 (83) 6.18 (3.72 to 10.30)
Poor role function 133 (11) 1.00 (reference) 76 (40) 2.06 (0.95 to 4.49)
Poor emotional function 174 (15) 1.00 (reference) 77 (40) 2.78 (1.55 to 4.98)
Symptomatic fatigue 226 (19) 1.00 (reference) 118 (61) 4.64 (2.73 to 7.88)
Symptomatic dyspnoea 481 (41) 1.00 (reference) 149 (78) 4.37 (2.54 to 7.49)

Frequency weighted for age and sex to match the national distribution in Sweden.

*Minor burden: Participants reporting ‘none’ or ‘a little’ burden of any cardiovascular disease. Others are grouped as ‘major burden’. Cardiovascular disease: Angina, atrial fibrillation, heart failure, hypertension or earlier myocardial infarction. Participants with multiple diagnosis (255).

†Poor or symptomatic: At least one response of ‘quite a bit’ or ‘very much’ on an item within a scale (physical, role and emotional function, fatigue and dyspnoea) or at least one response of 1-4 on one of the items in the global quality-of-life scale.

‡Adjusted for age, sex, education, comorbidity, tobacco smoking and physical activity.