Skip to main content
. 2012 Oct 17;2(5):e001231. doi: 10.1136/bmjopen-2012-001231

Table 3.

Multivariate models for lung function and both Alu and LINE-1 methylation*

  Alu LINE-1
β p Value Β p Value
FEV1 0.028 0.017 −0.015 0.08
FVC 0.027 0.06 −0.017 0.11
FEV1/FVC 0.3 0.057 −0.092 0.44
COPD 0.85 (0.71 to 1.03) 0.09 1.01 (0.89 to 1.15) 0.83

*Adjusted for age, height, race, BMI, pack-years of smoking, smoking status. Models with LINE-1 also include per cent lymphocytes.

BMI, body mass index; COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; LINE-1, long-interspersed nuclear elements.