Table 2.

Distribution of HMOX1 polymorphisms and α-globin gene deletion status among 942 children in the SIT Trial by genotype and allele class

−413A > T (rs2071746)		(GT)n(rs3074372): S/L		α-globin status
Genotype*	%	Genotype†	%	Genotype‡	%
AA	11.6	S/S	3.7	αα/αα	58.2
AT	42.1	S/L	25.2	−α/αα	36.6
TT	46.3	L/L	71.1	−α/-α	5.2

^*−413A > T results are in Hardy-Weinberg equilibrium (P = .369).

^†(GT)_n allele classes defined by number of repeats: S ≤ 25 repeats; and L > 25 repeats.

^‡Persons with αα/ααα genotypes carried no gene deletions and were grouped with αα/αα.