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. Author manuscript; available in PMC: 2012 Nov 5.
Published in final edited form as: Cancer Epidemiol. 2012 Apr 13;36(3):306–316. doi: 10.1016/j.canep.2012.03.001

Figure 4.

Figure 4

Estimated excess odds ratios per drink-year for esophageal adenocarcinoma (EAC), esophagogastric junctional adenocarcinoma (EGJA) and esophageal squamous cell carcinoma (ESCC) within categories of drinks per day (DPD) (square symbol), plotted at the category-specific mean DPD, for all data (left panels) and for #10 DPD (right panels). Bars represent 95% confidence intervals. For EAC and EGJA, model (1) included DPD effects estimated by restricted cubic splines with four interior knots at 0.2, 0.5, 3.0 and 10.5 DPD for EAC and at 0.1, 1.0, 2.0 and 7.0 for EGJA (solid line), and at 0.1, 0.3, 1.3 and 2.0 DPD for EAC and at 0.1, 0.2, 2.0 and 9.8 for EGJA for never and #10 DPD drinkers (dash line). For ESCC, model (1) included DPD effects defined by an exponential function (see text) fitted to all data (solid line) and to restricted data (dash line). Note the aspect ratio for EAC and EGJA panels was 2-times the aspect ratio for the ESCC panels. Data from the Barrett’s Esophagus and Esophageal Adenocarcinoma Consortium (BEACON).