Table 2.
Base-case assumptions on costs, and level and duration of lost utility for different events and health states (costs are given in 2010 prices)
| Type of test | Category | Costs (€) | Utilities lost | |
|---|---|---|---|---|
| Level | Duration | |||
| Invitation | 4.74 | 0 | – | |
| Primary cytology* | Laboratory costs | 21.77** | 0.006 | 2 weeks |
| Organisation | 11.23 | |||
| GP costs | 11.76 | |||
| Time/travel | 6.01 | |||
| Programme costs | 2.08 | |||
| Repeat cytology | GP costs | 22.21 | 0.006 | Time since last test*** |
| Laboratory costs | 26.54** | |||
| Time/travel | 6.01 | |||
| Primary HPV test**** | Laboratory costs | 33.87 | 0.006 | 2 weeks |
| Organisation | 11.23 | |||
| GP costs | 11.76 | |||
| Time/travel | 6.01 | |||
| Programme costs | 2.08 | |||
| Repeat HPV test | GP costs | 22.21 | 0.006 | Time since last test*** |
| Laboratory costs | 33.87 | |||
| Time/travel | 6.01 | |||
| Diagnosis and treatment pre-invasive stages | False positive referral | 284 | 0.005 | 0.5 year |
| CIN 1 | 886 | 0.03 | 0.5 year | |
| CIN 2 | 1312 | 0.07 | 1 year | |
| CIN 3 | 1536 | 0.07 | 1 year | |
| Diagnosis and treatment invasive cancer | FIGO 1A | 5031 | 0.062 | 5 years |
| FIGO 1B | 11 930 | 0.062 | 5 years | |
| FIGO 2+ (detected by screening) | 11 758 | 0.28 | 5 years | |
| FIGO 2+ (clinically detected) | 10 982 | 0.28 | 5 years | |
| Terminal care | 26 717 | 0.712 | 1 month | |
We assumed additional co-collection costs of €1 (for conventional cytology) or €0 (for LBC) to collect the material for a triage HPV test during a primary cytology test.
For LBC, the costs are €33.72 for a primary test and €38.49 for a repeat test.
The time since the last test can be 0 weeks (in the case of co-collection during the primary test), 2 weeks (if a woman is invited for a repeat test immediately after a positive primary test), 6 or 12 months.
We assumed additional co-collection costs of €1 (conventional cytology) or €3 (for LBC) to collect the material for a triage cytology test during a primary HPV test.