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. 2012 Jun;66(6):565–573. doi: 10.1111/j.1742-1241.2012.02918.x

Table 3.

Claims-based adherence and physician-reported adherence

Physician-reported adherence

Total patients (N = 214) Schizophrenia diagnosis codes only (n = 44) Bipolar disorder diagnosis codes only (n = 162)



Adherence Adherence Adherence



Claims-based Low (0–30%) Moderate (31–70%) High (71–100%) Kappa coeffi-cient p value Low (0–30%) Moderate (31–70%) High (71–100%) Kappa coeffi-cient p value Low (0–30%) Moderate (31–70%) High (71–100%) Kappa coeffi-cient p value
Low adherence (0–30%) 5 12 32 0.0572 .1908 0 0 7 0.0088 .9089 4 12 24 0.0478 .3522
Moderate adherence (31–70%) 2 13 50 0 1 9 2 12 38
High adherence (71–100%) 0 19 81 0 2 25 0 17 53

Kappa coefficient assesses the degree of agreement between physician-reported adherence and claims-based adherence; a large Kappa indicates a strong level of agreement. The Kappa test is used to test the null hypothesis of no agreement. The small value of Kappa and p value indicate no agreement between physician-reported adherence and claims-based adherence. There are eight patients with both schizophrenia and bipolar disorder diagnosis codes that are included only in the total patients’ adherence part of the above table.