Table 3.

Claims-based adherence and physician-reported adherence

	Physician-reported adherence
	Total patients (N = 214)					Schizophrenia diagnosis codes only (n = 44)					Bipolar disorder diagnosis codes only (n = 162)
	Adherence					Adherence					Adherence
Claims-based	Low (0–30%)	Moderate (31–70%)	High (71–100%)	Kappa coeffi-cient	p value	Low (0–30%)	Moderate (31–70%)	High (71–100%)	Kappa coeffi-cient	p value	Low (0–30%)	Moderate (31–70%)	High (71–100%)	Kappa coeffi-cient	p value
Low adherence (0–30%)	5	12	32	0.0572	.1908	0	0	7	0.0088	.9089	4	12	24	0.0478	.3522
Moderate adherence (31–70%)	2	13	50			0	1	9			2	12	38
High adherence (71–100%)	0	19	81			0	2	25			0	17	53

Kappa coefficient assesses the degree of agreement between physician-reported adherence and claims-based adherence; a large Kappa indicates a strong level of agreement. The Kappa test is used to test the null hypothesis of no agreement. The small value of Kappa and p value indicate no agreement between physician-reported adherence and claims-based adherence. There are eight patients with both schizophrenia and bipolar disorder diagnosis codes that are included only in the total patients’ adherence part of the above table.