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. Author manuscript; available in PMC: 2012 Nov 5.
Published in final edited form as: Nat Neurosci. 2011 Sep 11;14(10):1253–1259. doi: 10.1038/nn.2908

Figure 3.

Figure 3

Structures specific to α7 revealed by the α7–AChBP chimera. (a) Four regions of α7-specific residues near loops C (magenta) and F (red), indicated by I–IV. (b) Close-up of the signal transduction region beneath loop C. Alternative conformations of Arg182 are indicated by different colors. (c) Close-up of linkage region between loops C and F within the same subunit. (d,e) Glu185-Glu158-Asp160 triad spanning loop C of the principal subunit and loop F of the complementary subunit, in ribbon (d) and surface (e) representation. Positive and negative surface potentials are indicated by blue and red, respectively. (f) Close-up of glycan across from loop C. NAG, N-acetylglucosamine.