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. Author manuscript; available in PMC: 2012 Nov 5.
Published in final edited form as: Nat Neurosci. 2011 Sep 11;14(10):1253–1259. doi: 10.1038/nn.2908

Figure 6.

Figure 6

Molecular recognition of epibatidine. (a) Stereo view of the ligand-binding pocket from the side of the pentamer showing the position of epibatidine (Epi) in the aromatic cage. The protein is in ribbon style and the epibatidine molecule is shown with the FoFc electron density contoured at the 3.0-σ level. (b) Stereo view of the ligand-binding pocket from above the pentamer. This view highlights hydrogen-bond interactions and interactions with the complementary face of the binding site between epibatidine and the receptor chimera.