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Alkaline phosphatase (ALP) activity of human mesenchymal stem cells (hMSCs) cultured on dorsal shield and lamellar blocks of natural cuttlefish bone. Cells were cultured for 5 days in the presence or absence of an osteogenic stimulant (OS). ALP activity significantly increased in hMSCs cultured on both dorsal shield and lamellar blocks. Values are expressed as the mean ± SD. Significance was determined at *p < 0.05 when compared with non-OS-treated cells.
