Table 3. Sequence similarity and structural similarity in the icosahedral asymmetric units of picornaviruses.

Lower left portion of table: root-mean-square deviations (r.m.s.d.s; ) of superimposed C atoms of the respective three-dimensional structures. The second number (following the slash) indicates the percentage of equivalent amino acids used for calculating the r.m.s.d. with respect to the number of residues in the smaller of the two structures being compared. The icosahedral asymmetric unit consisting of subunits VP1, VP2, VP3 and VP4 was used as a rigid body in all cases. The program O (Jones et al., 1990 ▶) was used for superposition of the molecules. The cutoff for inclusion of residues in the r.m.s.d. calculation was 3.8. Upper right portion of table: percentage of equivalent residues that are identical.

	EV71	Bovine enterovirus (BEV)	Coxsackievirus B3 (CVB3)	HRV14	HRV1a	Echovirus 7	Poliovirus 1
EV71		49	43	42	40	41	41
BEV	1.0/94		45	44	43	45	43
CVB3	1.1/90	1.0/94		48	46	72	54
HRV14	1.2/92	1.1/93	1.0/94		49	46	48
HRV1a	1.1/89	1.1/91	0.9/92	1.0/92		45	44
Echovirus 7	1.1/89	1.1/94	0.7/98	1.1/95	1.0/93		53
Poliovirus 1	1.1/88	1.1/93	1.0/95	1.0/95	1.1/93	1.0/95