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. 2012 Oct 4;345:e5945. doi: 10.1136/bmj.e5945

Table 3.

 Data regarding HIV incidence and estimate of effect of methadone detoxification treatment in relation to HIV transmission among people who inject drugs

Exposure variable HIV seroconversions/person years HIV incidence per 100 py (95% CI) Rate ratio (95% CI)
Vanichseni et al 200111 45 day detoxification in past 4 months; methadone maintenance treatment Detox: 106/1730.6; MMT: 24/488.3 6.1 (5.0 to 7.4); 4.9 (3.1 to 7.3) 1.2 (0.7 to 1.8)
Nelson et al 20028 Detoxification in past 6 months (yes/no) Yes: 33/778; No: 243/8033 Yes: 4.24*; No: 3.03 1.4 (0.97 to 2.02)
Suntharasamai et al 200917 45-day methadone detoxification in past 6 months (yes/no) Yes: 89/1666; No: 121/5130 Yes: 5.3 (4.3-6.6); No: 2.4 (2.0-2.8) 2.4 (1.8 to 3.3)
Bruneau, 2012 (unpublished) Methadone detoxification in past 6 months (yes/no) NA NA 0.73 (0.18 to 2.99)

NA=not available.

*95% confidence intervals were not reported.