Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
HER2 expression is maintained upon ex vivo culture of lapatinib-treated brain metastatic tumor cells. 231-BR-HER2 cells were injected into immunocompromised mice, treated with either 100 mg/kg lapatinib twice daily or vehicle. At necropsy, tumor cells were cultured ex vivo from brains of lapatinib-treated (L) or vehicle-treated (V) mice. The HER2 expression of lysates of each culture was determined by western blot, using α-tubulin as a loading control.
