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. Author manuscript; available in PMC: 2012 Nov 5.
Published in final edited form as: Addiction. 2010 Apr;105(4):709–718. doi: 10.1111/j.1360-0443.2009.02843.x

Figure 1.

Figure 1

Figure 1

(A) Mean drug progressive ratio breakpoints for intravenous test doses across all buprenorphine maintenance doses. (B) Mean progressive ratio breakpoints for test drug stratified by buprenorphine maintenance dose. BupNx, buprenorphine/naloxone; Bup, buprenorphine. * P < 0.01 compared with placebo. †P < 0.01 compared with heroin. ‡P ≤ 0.055 compared with heroin. §P < 0.03 compared with 8 mg buprenorphine maintenance dose. ‖P < 0.05 compared with 2 mg buprenorphine maintenance dose.