Fig. 1.
A central role for blocking recombination in sex-determination and speciation. A. Conversion of non-allelic sex-determination to allelic determination, through divergence by (1) mutations (* marks) or (2) a chromosomal inversion event (arrows). B. Gradual divergence through mutations leads to sub-populations unable to mate with the original population. C. When rare illegitimate recombination does occur within the MAT locus of heterothallic species, this can lead to the formation of new species that are homothallic. One of several possible recombination and chromosomal rearrangements is illustrated.