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. 2005 Oct 11;15(5):543–553. doi: 10.1007/s00586-005-1027-y

Table 5.

Criteria used for grading evidence and strength of recommendations

Use of criteria in guidelines Totala, n (%)
Not used, n (%) Used but not defined, n (%) Used and defined, n (%)
Criteria related to evidence
Susceptibility to bias of studies 6 (43) 0 8 (57)b 14 (100)
Quality of studies 1 (7) 9 (64) 4 (29) 14 (100)
How precise results are 13 (93) 1 (7) 0 14 (100)
Heterogeneity of results 8 (57) 6 (43) 0 14 (100)
Criteria related to outcomes
Size of beneficial effect 8 (57) 6 (43) 0 14 (100)
Risks 11 (79) 2 (14) 1 (7) 14 (100)
Costs 12 (86) 2 (14) 0 14 (100)

aThere was no scale for grading evidence or strength of recommendations in three guidelines

bThe best study designs were usually considered to be randomized clinical trials