Table 4.
Analyze network' algorithm results for a plasma proteome from a mouse ovarian cancer model
| No | Network | GO Processes | Total nodes | Seed nodes | Pathways | p-Value | zScore | gScore |
|---|---|---|---|---|---|---|---|---|
| 1 | Factor H, APOF, Cathepsin Z, TIG2, SSB-2 | positive regulation of cell adhesion (15.6%; 1.020e-08), regulation of biological quality (44.4%; 1.296e-08), response to inorganic substance (22.2%; 7.552e-08), wound healing (17.8%; 2.420e-07), anatomical structure morphogenesis (35.6%; 3.159e-07) | 50 | 14 | 2 | 1.270E-29 | 54.15 | 56.65 |
| 2 | Fetuin-A, IBP4, Thrombospondin 1, KNG, SERPINA3 (ACT) | response to wounding (39.6%; 8.503e-15), regulation of biological quality (54.2%; 2.556e-13), response to stimulus (72.9%; 3.053e-12), inflammatory response (29.2%; 3.365e-12), response to stress (52.1%; 1.913e-11) | 50 | 14 | 0 | 2.470E-29 | 53.05 | 53.05 |
| 3 | Calgranulin A, Calgranulin B, VCAM1, Cathepsin D, NOTCH2 | positive regulation of cellular process (67.4%; 1.338e-15), response to stress (62.8%; 5.497e-15), positive regulation of biological process (67.4%; 1.566e-14), multicellular organismal process (83.7%; 5.605e-14), developmental process (74.4%; 9.693e-14) | 50 | 13 | 0 | 8.090E-27 | 49.24 | 49.24 |
| 4 | Thrombospondin 1, CNBP, AKR1C1, Coagulation factor XI, NOV | regulation of biological quality (58.8%; 1.894e-11), multicellular organismal process (79.4%; 8.590e-10), regulation of multicellular organismal process (44.1%; 1.560e-08), response to stress (50.0%; 7.234e-08), positive regulation of cellular component organization (23.5%; 1.432e-07) | 50 | 11 | 2 | 3.690E-22 | 42.49 | 44.99 |
An excerpt of AN network list (from MetaCore) constructed from the list of 58 proteins derived from a plasma proteome of a mouse ovarian cancer model. For a complete description of each column refer to network statistics please see "3.2.2. Prioritization of sub-networks".