Table 4. Anthropometric and biochemical characteristics and mRNA expression of FABP1, FABP4 and FABP5 in a subgroup of morbidly obese and morbidly obese IR patients with liver biopsies.
| Morbid no IR | Morbid IR | |
| n = 7 | n = 10 | |
| Age (years) | 43.43±8.73 | 44.30±8.26 |
| Waist(cm) | 123.78±13.37 | 125.90±9.87 |
| Hip (cm) | 140.58±8.54 | 144.75±9.17 |
| BMI (Kg/m2 ) | 41.76±3.70 | 45.36±6.47 |
| SBP (mm Hg) | 106.42±20.75 | 114.24±19.31 |
| DBP (mm Hg) | 91.42±10.69 | 87.50±11.36 |
| Insulin (µIU/ml) | 9.15±2.16 | 25.15±7.26* |
| Glucose (mM) | 5.1±0.6 | 5.4±0.7 |
| Cholesterol (mM) | 5.42±1.2 | 5.37±2.1 |
| Triglycerides (mM) | 1.4±0.4 | 1.3±0.8 |
| HDL-C (mM) | 1.0±0.3 | 1.1±0.7 |
| LDL-C (mM) | 2.6±1.0 | 2.2±0.7 |
| HOMA-IR | 2.09±0.54 | 6.03±2.18* |
| FABP4 mRNA | 0.78±0.48 | 2.28±1.27* |
| FABP1 mRNA | 1.01±0.20 | 1.63±0.75* |
| FABP5 mRNA | 0.25±0.19 | 1.65±1.28* |
Data are mean ± SD;
*
indicates significant differences between the means of the two groups.
(P<0.05). BMI, body mass index; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; HOMA-IR, Homeostasis model assessment of insulin resistance; SBP, Systolic Blood Pressure; DBP, Diastolic Blood Pressure.