Table 3.

Genes linked to genomic instability

Biological Process	Gene Symbol	Gene Name	Contrast	log2 (Fold Change)
DNA damage response and repair downregulation	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	A1789TvsWT	−0.4309041
	SMC1A	structural maintenance of chromosomes 1A	A1789TvsWT MutvsWT	−0.2754507 −0.2640263
	PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	A1789TvsWT	−0.4286825
	AHNAK	AHNAK nucleoprotein	A1789TvsWT M1775RvsWT MutvsWT	−0.3988113
				−0.3103867
				−0.3940570
	SOD2	superoxide dismutase 2, mitochondrial	M1775RvsWT MutvsWT	−0.3376169
				−0.2502831
DNA damage response and repair upregulation	MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	A1789TvsWT	0.3293561
	TERF1	telomeric repeat binding factor (NIMA-interacting) 1	MutvsWT	0.2790907
	OBFC2A	oligonucleotide/oligosaccharide-binding fold containing 2A	M1775RvsWT	0.3666172
	OBFC2B	oligonucleotide/oligosaccharide-binding fold containing 2B	A1789TvsWT MutvsWT	0.4070777
				0.3417360