Table 1.
Subjects’ characteristics for CLCA1 mRNA expression in induced sputum
| Non-smokers | Smokers without COPD | COPD | |
|---|---|---|---|
| Number of subjects (M / F) |
13 (9 / 4) |
5 (5 / 0) |
20 (20 / 0) |
| Age (yrs) |
29.8 ± 2.2 |
33.0 ± 4.9 |
72.3 ± 1.1 **†† |
| Current / ex-smokers |
- |
5 / 0 |
4 / 16 |
| Brinkman index (pack·years) |
- |
10.0 ± 2.4 |
52.1 ± 3.6 |
| VC (%predicted) |
99.0 ± 3.7 |
98.1 ± 2.2 |
97.8 ± 4.1 |
| FEV1 (L) |
3.5 ± 0.2 |
4.0 ± 0.3 |
1.4 ± 0.1 **†† |
| FEV1 / FVC (%) |
86.6 ± 1.5 |
88.4 ± 3.6 |
47.9 ± 2.0 **†† |
| FEV1 (%predicted) | 96.1 ± 3.3 | 101.7 ± 6.0 | 63.9 ± 5.7 **†† |
Results are means ± SEMs. Comparisons between groups were made by Student's t-tests (** p ≤ 0.01, compared with non-smokers; †† p ≤ 0.01, compared with smokers without COPD.).